Research Catalog
High-purity, structurally verified peptide sequences for advanced laboratory and pre-clinical applications.
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Metabolic
MOTS-c
≥99.3% HPLC Verified$70.00/ vial
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For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.
What is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the Twelve S rRNA-c) is a synthetic 16-amino acid peptide encoded in the mitochondrial genome. With the molecular formula C₁₀₁H₁₅₂N₂₈O₂₂S₂ and a molecular weight of 2174.6 g/mol (CAS: 1627580-64-6), MOTS-c represents a unique mitochondrial-derived peptide with metabolic regulatory functions.
Amino Acid Sequence:
MRWQEMGYIFYPRKLRClassification: Mitochondrial-Derived Peptide (MDP)FGF21 PathwayAMPK Signaling
Specifications
Published Research
Lee et al. (2015) discovered MOTS-c and characterized its role in metabolic regulation and AMPK activation in skeletal muscle cells (PMID: 26546794).
PMID: 26546794VERIFY PMIDReynolds et al. (2016) investigated MOTS-c's effects on FGF21 expression and metabolic signaling in adipocyte cultures (PMID: 27304508).
PMID: 27304508VERIFY PMIDMechanism of Action
AMPK Pathway
AMP-activated protein kinaseMOTS-c activates AMPK signaling, influencing cellular energy metabolism in muscle and fat cell models (PMID: 26546794).
FGF21 Expression
Fibroblast growth factor 21Research indicates MOTS-c increases FGF21 expression, affecting metabolic gene networks in adipose tissue cultures (PMID: 27304508).
Storage & Handling
Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Mitochondrial-derived peptide with unique origin and metabolic functions.
Research Use Only
All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
