Research Catalog
High-purity, structurally verified peptide sequences for advanced laboratory and pre-clinical applications.
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Cognitive
Semax
≥99.5% HPLC Verified$40.00/ vial
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For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.
What is Semax?
Semax is a synthetic heptapeptide derived from the adrenocorticotropic hormone (ACTH) fragment 4-10 with modifications. With the molecular formula C₃₇H₅₁N₉O₁₀ and a molecular weight of 812.9 g/mol (CAS: 80714-61-0), Semax consists of the sequence Met-Glu-His-Phe-Pro-Gly-Pro with an N-terminal proline and C-terminal glycine-proline added.
Amino Acid Sequence:
Pro-Gly-Pro-Glu-His-Phe-MetClassification: ACTH Fragment AnalogBDNF/TrkB PathwayNeurotrophic Factors
Specifications
Published Research
Ashmarin et al. (2006) investigated Semax's effects on BDNF expression and TrkB receptor activation in neuronal cell cultures (PMID: 16445185).
PMID: 16445185VERIFY PMIDMedvedeva et al. (2008) characterized Semax's effects on gene expression profiles and neurotrophic factor production in brain tissue models (PMID: 18841466).
PMID: 18841466VERIFY PMIDMechanism of Action
BDNF/TrkB Signaling
Neurotrophin receptor activationSemax increases brain-derived neurotrophic factor expression and activates TrkB receptors in neuronal cultures (PMID: 16445185).
Gene Expression
Transcriptional regulationResearch demonstrates Semax modulates expression of genes involved in neuroplasticity and neurotrophic factor production (PMID: 18841466).
Storage & Handling
Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Derived from ACTH fragment 4-10 with neuroprotective modifications.
Research Use Only
All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
