What is TB500 used for?

TB500 is a synthetic peptide compound studied in laboratory research settings. Scientific literature has explored its properties in preclinical studies. It is not approved for human use.

What purity level does Ever Vital's TB500 have?

Ever Vital supplies TB500 at 99%+ purity, verified by third-party HPLC and mass spectrometry analysis. Certificates of Analysis are available upon request.

How is TB500 supplied?

TB500 is supplied as a lyophilized powder in sealed research-grade vials, intended for in vitro and laboratory research use only.

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TB500

Name: TB500
Brand: Ever Vital
SKU: EV-TB500

≥99% HPLC Verified

$70.00/ vial

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For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.

CAS Number885340-08-9

Molecular FormulaC₃₈H₆₈N₁₀O₁₄

Molecular Weight868.99 g/mol

Purity≥99% (HPLC)

Storage−20°C · Lyophilized

FormLyophilized Powder

Ever Vital lists TB-500 (Thymosin Beta-4 Fragment) as a synthetic 43-amino acid peptide that reproduces the active region of the naturally occurring Thymosin Beta-4 protein. Its molecular formula is C₂₁₂H₃₅₀N₅₆O₇₈S and its molecular weight is 4963.5 g/mol (CAS: 77591-33-4). The name functions as the research designation for the fragment that holds the parent protein's primary bioactive sequence.

Amino Acid Sequence

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH

Actin-Binding Peptide FragmentActin CytoskeletonG-Actin Binding

Mechanism of Action

Actin CytoskeletonG-actin sequestration

Cell-culture models show TB-500 binding monomeric G-actin, which sets actin polymerization and broader cytoskeletal dynamics.

Cell MigrationIntegrin signaling

Reported effects on cell motility trace back to interactions with integrin receptors and focal adhesion dynamics.

Recommended Storage−20°C · Lyophilized

FormLyophilized (freeze-dried) powder

Temperature-20°C for long-term storage

Light SensitivityProtect from direct light

StabilityStable for 24 months when stored properly

NotesMaintain at -20°C in original lyophilized form until laboratory use; minimize temperature cycling.

What is TB-500?

Amino Acid Sequence:

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH

Classification: Actin-Binding Peptide FragmentActin CytoskeletonG-Actin Binding

Specifications

CAS Number	885340-08-9
Molecular Formula	C38H68N10O14
Molecular Weight	868.99 g/mol
Purity	≥99% (HPLC verified)
Form	Lyophilized powder
Storage	−20°C · Lyophilized

Mechanism of Action

Actin Cytoskeleton

G-actin sequestration

Cell-culture models show TB-500 binding monomeric G-actin, which sets actin polymerization and broader cytoskeletal dynamics.

Cell Migration

Integrin signaling

Reported effects on cell motility trace back to interactions with integrin receptors and focal adhesion dynamics.

Storage & Handling

Temperature:-20°C for long-term storage

Light Sensitivity:Protect from direct light

Stability Duration:Stable for 24 months when stored properly

Maintain at -20°C in original lyophilized form until laboratory use; minimize temperature cycling.

Related Compounds

BPC-157 GHK-Cu Thymosin Alpha-1

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

TB500

Compound Profile