Research Catalog
High-purity, structurally verified peptide sequences for advanced laboratory and pre-clinical applications.
Free Shipping$250 away
←Back to Collection
Healing
Thymosin Alpha-1
≥99.6% HPLC Verified$75.00/ vial
1
Save to Wishlist
For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.
What is Thymosin Alpha-1?
Thymosin Alpha-1 is a synthetic version of a naturally occurring thymic peptide originally isolated from thymosin fraction 5. With the molecular formula C₁₂₉H₂₁₅N₃₃O₅₅ and a molecular weight of 3108.3 g/mol (CAS: 62304-98-7), Thymosin Alpha-1 is a 28-amino acid peptide representing the N-terminal acetylated fragment of prothymosin alpha.
Amino Acid Sequence:
Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-AsnClassification: Thymic PeptideTLR ReceptorsT-Cell Receptors
Specifications
Published Research
Romani et al. (2006) characterized Thymosin Alpha-1's interactions with Toll-like receptors and dendritic cell activation markers in vitro (PMID: 16683274).
PMID: 16683274VERIFY PMIDKing et al. (2008) reviewed Thymosin Alpha-1's receptor binding properties and intracellular signaling pathways in immune cell models (PMID: 18423086).
PMID: 18423086VERIFY PMIDMechanism of Action
TLR Signaling
MyD88-dependent pathwayThymosin Alpha-1 interacts with Toll-like receptors, activating MyD88-dependent signaling and NF-κB translocation in immune cell cultures (PMID: 16683274).
T-Cell Activation
TCR signaling enhancementResearch indicates the peptide enhances T-cell receptor signaling and T-cell differentiation markers in lymphocyte cultures (PMID: 18423086).
Storage & Handling
Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Acetylated at the N-terminus for enhanced stability.
Research Use Only
All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
