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GH Secretagogues

CJC-1295 no DAC

99% HPLC Verified
$55.00/ vial
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For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.

CJC-1295 no DAC
CAS Number446036-97-1
Molecular FormulaC152H252N44O42
Molecular Weight3367.9 g/mol
Purity99% (HPLC)
Storage−20°C · Lyophilized
FormLyophilized Powder

Ever Vital catalogues CJC-1295 without DAC (Drug Affinity Complex), also called Modified GRF (1-29), as a synthetic analog of growth hormone-releasing hormone (GHRH). It carries the molecular formula C₁₅₂H₂₅₂N₄₄O₄₂ and a molecular weight of 3367.9 g/mol (CAS: 446036-97-1). The chain reproduces the first 29 amino acids of GHRH, reworked at positions 2 (D-Ala), 8 (Ala), 15 (Gln), 16 (Leu), 23 (Tyr), 24 (Gln), and 28 (Ser).

Amino Acid SequenceTyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Ala-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser
GHRH AnalogGHRH ReceptorGHS-R1a

Mechanism of Action

GHRH ReceptorcAMP/PKA signaling

In cell culture, CJC-1295 NO DAC docks onto GHRH receptors across pituitary somatotrophs, switching on adenylate cyclase and pushing intracellular cAMP higher.

Growth Hormone ReleaseIntracellular calcium mobilization

Through that GHRH receptor activation, the peptide sets off intracellular calcium release and growth hormone secretion.

Recommended Storage−20°C · Lyophilized
FormLyophilized (freeze-dried) powder
Temperature-20°C for long-term storage
Light SensitivityProtect from direct light
StabilityStable for 24 months when stored properly
NotesThe NO DAC formulation has shorter half-life than CJC-1295 with DAC in biochemical assays.

What is CJC-1295 NO DAC?

Ever Vital catalogues CJC-1295 without DAC (Drug Affinity Complex), also called Modified GRF (1-29), as a synthetic analog of growth hormone-releasing hormone (GHRH). It carries the molecular formula C₁₅₂H₂₅₂N₄₄O₄₂ and a molecular weight of 3367.9 g/mol (CAS: 446036-97-1). The chain reproduces the first 29 amino acids of GHRH, reworked at positions 2 (D-Ala), 8 (Ala), 15 (Gln), 16 (Leu), 23 (Tyr), 24 (Gln), and 28 (Ser).

Amino Acid Sequence:Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Ala-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser
Classification: GHRH AnalogGHRH ReceptorGHS-R1a

Specifications

CAS Number446036-97-1
Molecular FormulaC152H252N44O42
Molecular Weight3367.9 g/mol
Purity≥99% (HPLC verified)
FormLyophilized powder
Storage−20°C · Lyophilized

Mechanism of Action

GHRH Receptor

cAMP/PKA signaling

In cell culture, CJC-1295 NO DAC docks onto GHRH receptors across pituitary somatotrophs, switching on adenylate cyclase and pushing intracellular cAMP higher.

Growth Hormone Release

Intracellular calcium mobilization

Through that GHRH receptor activation, the peptide sets off intracellular calcium release and growth hormone secretion.

Storage & Handling

Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
The NO DAC formulation has shorter half-life than CJC-1295 with DAC in biochemical assays.

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.

Scientific Context

Related Research & Analysis

GH Secretagogues

Growth Hormone Secretagogue (GHS) Peptides: Comparative Research Specifications

Comparative analysis of GHS peptides including CJC-1295, Ipamorelin, Sermorelin, and Tesamorelin. Molecular weights, binding sequences, and published receptor findings.

Read Full Article