Research Catalog
High-purity, structurally verified peptide sequences for advanced laboratory and pre-clinical applications.
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GH Secretagogues
FOXO4
≥99.0% HPLC Verified$280.00/ vial
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For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.
What is FOXO4-DRI?
FOXO4-DRI is a D-amino acid retro-inverso peptide (DRI) and p53-interaction domain analog. With the molecular formula C₂₂₈H₃₉₀N₈₆O₇₅S₂ and a molecular weight of 5358.1 g/mol (CAS: 1449830-41-4), it structurally mimics endogenous peptides while extending its sequence.
Amino Acid Sequence:
D-amino acid sequence matching FOXO4-p53 binding domainClassification: D-Amino Acid Retro-Inverso Peptide (Dri)FOXO4-p53 InteractionSenescence-associated pathways
Specifications
Published Research
Bourgeois et al. (2025) investigated FOXO4-DRI's binding affinity and receptor interactions in vitro (PMID: 40593617).
PMID: 40593617Meng et al. (2021) investigated FOXO4-DRI's binding affinity and receptor interactions in vitro (PMID: 34877934).
PMID: 34877934Mechanism of Action
FOXO4-p53 Interaction
Receptor interactionPublished research demonstrates FOXO4-DRI modulates targeted signaling cascades within cell tissue models (PMID: 40593617).
Senescence-associated pathways
Signaling cascadeIn cellular environments, FOXO4-DRI exhibits selective binding and corresponding pathway activation (PMID: 34877934).
Storage & Handling
Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Research-grade sequence verification via standard assays.
Related Compounds
Research Use Only
All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
Related Research Compounds
Scientific Context