Research Catalog
High-purity, structurally verified peptide sequences for advanced laboratory and pre-clinical applications.
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GH Secretagogues
Ipamorelin
≥99.5% HPLC Verified$40.00/ vial
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For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.
What is Ipamorelin?
Ipamorelin is a synthetic pentapeptide and selective growth hormone secretagogue. With the molecular formula C₃₈H₄₉N₉O₅ and a molecular weight of 711.9 g/mol (CAS: 170851-70-4), Ipamorelin is derived from the growth hormone-releasing peptide (GHRP) family and exhibits unique selectivity for growth hormone release.
Amino Acid Sequence:
Aib-His-D-2-Nal-D-Phe-Lys-NH2Classification: Selective GH SecretagogueGHS-R1a (Ghrelin Receptor)Growth Hormone Secretagogue Receptor
Specifications
Published Research
Raun et al. (1998) characterized Ipamorelin's selective binding to GHS-R1a receptors and its effects on growth hormone release in pituitary cell cultures (PMID: 10698741).
PMID: 10698741VERIFY PMIDJohansen et al. (2002) investigated Ipamorelin's receptor binding kinetics and signaling pathways in CHO cells expressing GHS-R1a (PMID: 11916262).
PMID: 11916262VERIFY PMIDMechanism of Action
GHS-R1a Receptor
Ghrelin receptor agonismIpamorelin selectively activates the ghrelin receptor (GHS-R1a) on somatotrophs, stimulating growth hormone release without significantly affecting other pituitary hormones (PMID: 10698741).
Intracellular Signaling
IP3/DAG/Ca2+ cascadeReceptor activation triggers phospholipase C-mediated signaling, increasing intracellular calcium and activating protein kinase C (PMID: 11916262).
Storage & Handling
Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Selective mechanism distinguishes Ipamorelin from non-selective GHRP compounds.
Related Compounds
Research Use Only
All compounds are sold strictly for laboratory research use. Not for human or animal consumption. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
Related Research Compounds
Scientific Context