GLP-1
≥99% HPLC VerifiedFor in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.

What is GLP-1?
Ever Vital catalogues GLP-1 (Semaglutide) as a synthetic analog of human glucagon-like peptide-1 (GLP-1) sharing 94% homology with native GLP-1. It carries the molecular formula C₁₈₇H₂₉₁N₄₅O₅₉ and a molecular weight of 4113.6 g/mol (CAS: 910463-68-2). The design adds a C18 fatty di-acid side chain to lysine at position 26, substitutes at positions 8 (Aib) and 34 (Arg), and truncates the C-terminus.
His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEA-AEEA-γ-Glu-eicosanedioic acid)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-GlySpecifications
Mechanism of Action
GLP-1 Receptor
Receptor interactionAcross cell-tissue models, the research record has GLP-1 modulating signaling cascades at the GLP-1 receptor.
Gs-protein coupled signaling
Signaling cascadeIn cellular environments the peptide shows selective binding and the corresponding Gs-protein coupled pathway activation.
Storage & Handling
Related Compounds
Research Use Only
All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.
Scientific Context


