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Metabolic

GLP-3

≥99.3 HPLC% HPLC Verified
$55.00/ vial
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For in vitro laboratory research use only. Not for human or veterinary use. Not evaluated by the FDA. Must be 21+ to purchase.

GLP-3
CAS Number2381089-83-2
Molecular FormulaC221H342N46O68
Molecular Weight4731.33 g/mol
Purity≥99.3 HPLC% (HPLC)
Storage−20°C · Lyophilized
FormLyophilized Powder

GLP-3 is a retatrutide-class GLP-1/GIP/glucagon triple receptor agonist research peptide with the molecular formula C₂₂₁H₃₄₂N₄₆O₆₈ and a molecular weight of 4731.33 g/mol (CAS: 2381089-83-2), studied in pancreatic beta-cell and adipocyte models for concurrent GLP-1R, GIPR, and glucagon receptor signal transduction. Supplied at ≥99.3% HPLC purity as a lyophilized powder for in vitro research use only.

Amino Acid SequenceProprietary multi-receptor agonist sequence
Triple GLP-1/GIP/Glucagon Receptor AgonistGLP-1 Receptor (GLP-1R)GIP Receptor (GIPR)Glucagon Receptor (GCGR)

Mechanism of Action

Triple Receptor Co-AgonismGLP-1R/GIPR/GCGR simultaneous activation

GLP-3 activates three incretin/glucagon receptors concurrently, engaging distinct cAMP pathways in beta-cell and adipocyte culture models.

Recommended Storage−20°C · Lyophilized
FormLyophilized (freeze-dried) powder
Temperature-20°C for long-term storage
Light SensitivityProtect from direct light
StabilityStable for 24 months when stored properly
NotesResearch-grade sequence verification via standard assays.

What is GLP-3?

GLP-3 is a retatrutide-class GLP-1/GIP/glucagon triple receptor agonist research peptide with the molecular formula C₂₂₁H₃₄₂N₄₆O₆₈ and a molecular weight of 4731.33 g/mol (CAS: 2381089-83-2), studied in pancreatic beta-cell and adipocyte models for concurrent GLP-1R, GIPR, and glucagon receptor signal transduction. Supplied at ≥99.3% HPLC purity as a lyophilized powder for in vitro research use only.

Amino Acid Sequence:Proprietary multi-receptor agonist sequence
Classification: Triple GLP-1/GIP/Glucagon Receptor AgonistGLP-1 Receptor (GLP-1R)GIP Receptor (GIPR)Glucagon Receptor (GCGR)

Specifications

CAS Number2381089-83-2
Molecular FormulaC221H342N46O68
Molecular Weight4731.33 g/mol
Purity≥≥99.3 HPLC% (HPLC verified)
FormLyophilized powder
Storage−20°C · Lyophilized

Mechanism of Action

Triple Receptor Co-Agonism

GLP-1R/GIPR/GCGR simultaneous activation

GLP-3 activates three incretin/glucagon receptors concurrently, engaging distinct cAMP pathways in beta-cell and adipocyte culture models.

Storage & Handling

Temperature:-20°C for long-term storage
Light Sensitivity:Protect from direct light
Stability Duration:Stable for 24 months when stored properly
Research-grade sequence verification via standard assays.

Research Use Only

All compounds are sold strictly for laboratory research use. Not for human use. These products are not drugs, supplements, or food. Statements have not been evaluated by the FDA. Must be 21+ to purchase. This compound is intended exclusively for in vitro laboratory research. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease.